The safety of Trulance has been well studied
Tell your doctor if you experience any side effects while taking Trulance. In clinical studies, 5% of people with Chronic Idiopathic Constipation (CIC) and 4.3% of people with Irritable Bowel Syndrome with Constipation (IBS-C) taking Trulance experienced diarrhea.
Diarrhea is the most common side effect and can sometimes be severe. Diarrhea often begins within the first 4 weeks of Trulance treatment. If you get severe diarrhea, stop taking Trulance and call your doctor right away.
Do not take Trulance if a doctor has told you that you have a bowel blockage (intestinal obstruction).
Studies indicated that Trulance is not expected to interact with other medications.