Trulance for IBS-C

Trulance can help you have more regular, well-formed bowel movements^*

^*Versus placebo (sugar pill) group

How once-daily Trulance can help with Irritable Bowel Syndrome with Constipation (IBS-C):

reduce abdominal pain
and increase frequency Improve your form

Trulance helped patients have less abdominal pain

Taking Trulance can also help you strain less when you have a bowel movement (BM).

Trulance can help people with IBS-C have more regular,
well-formed BMs

Trulance can help people have “Normal” (smooth, soft sausage or snake-shaped) bowel movements

Trulance can help provide relief from your constipation in as little as 24 hours^†

For continued results, take Trulance every day^‡

In 12-week clinical trials, many patients taking Trulance maintained their constipation relief with continued use.

^†In clinical studies, results seen without the use of laxatives.

^‡Or as directed by your doctor.

The American College of Gastroenterology (ACG), one of the leading organizations of gastroenterologists, has given Trulance, as part of a class of drugs, a strong recommendation to treat global IBS-C symptoms. This is based on the highest level of clinical trial data.

If you want to learn more about the clinical data supporting the recommendation to see if Trulance is right for you, talk to your doctor.

BRISTOL STOOL FORM SCALE

Type #1

Separate hard lumps, like nuts. Hard to pass.

Type #2

Sausage-shaped but lumpy.

Type #3

Like a sausage but with cracks on surface.

Type #4

Like a sausage or snake, smooth & soft.

Type #5

Soft blobs with clear-cut edges.

Type #6

Fluffy pieces with ragged edges, a mushy stool.

Type #7

Watery, no solid pieces. Entirely liquid.

Adapted from Lewis SJ, Heaton KW. Stool form scale as a useful guide to intestinal transit time. Scand J Gastroenterol. 1997;32:920-924.

Identify your treatment goals with the Bristol Stool Form Scale

The Bristol Stool Form Scale is a visual representation of the 7 different types of Bowel Movements that you can have. A “4” bowel movement—described by the scale as smooth, soft sausage or snake-shaped—is free of lumps or excess liquid and is considered well-formed. A “Type 1 or 2” is often considered constipation, while a “Type 6 or 7” is often considered diarrhea.

While it might seem awkward to talk about, telling your doctor which type or types of stool you typically have can help you both create a treatment plan that works for you and your body.

Go to the doctor discussion guide

About Trulance

How it works

What Is Trulance?

Trulance^® (plecanatide) 3 mg tablets is a prescription medicine used in adults to treat Irritable Bowel Syndrome with Constipation (IBS-C) and Chronic Idiopathic Constipation (CIC). Chronic means the constipation is long lasting. “Idiopathic” means the cause of the constipation is unknown. It is not known if Trulance is safe and effective in children less than 18 years of age.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about Trulance?

Do not give Trulance to children who are less than 6 years of age. It may harm them.
You should not give Trulance to children 6 years to less than 18 years of age. It may harm them.
Do not take Trulance if a doctor has told you that you have a bowel blockage (intestinal obstruction).

Before you take Trulance, tell your doctor:

If you have any other medical conditions.
If you are pregnant or plan to become pregnant. It is not known if Trulance will harm your unborn baby.
If you are breastfeeding or plan to breastfeed. It is not known if Trulance passes into your breast milk. Talk with your doctor about the best way to feed your baby if you take Trulance.
About all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the common side effects of Trulance?

Diarrhea is the most common side effect and can sometimes be severe. Diarrhea often begins within the first 4 weeks of Trulance treatment. Stop taking Trulance and call your doctor right away if you get severe diarrhea.

These are not all the possible side effects of Trulance. Tell your doctor if you have any side effect that bothers you or that does not go away.

You are encouraged to report side effects to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088 or you can report side effects to Bausch Health at 1-877-361-2719.

Please also see Medication Guide within the full Prescribing Information.

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